Peroxisome Proliferator-Activated Receptors by Jihan A. Youssef
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Peroxisome Proliferator-Activated Receptors

Peroxisome Proliferator-Activated Receptors


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International Edition


About the Book

I. Introduction

II. History of PPAR Discovery

A. Peroxisomes

B. Peroxisomal biogenesis and diseases

C. Peroxisome proliferation

III. Peroxisome Proliferator-Activated Receptors

A. Chromosomal location and gene polymorphism

i. PPARa

ii. PPARb/d

iii. PPARg

B. Protein structure

i. N-terminal end (A/B domain)

ii. DNA binding domain (DBD, C domain)

iii. Hinge region (D domain)

iv. Carboxyl terminal end (E/F domain)

IV. PPAR Ligands

A. Endogenous ligands

B. Exogenous PPAR modulators

V. Tissue Distribution and Versatile Functions of PPARs

A. Neurological functions of PPARs

B. PPARs and the cardiovascular system

C. PPARs in pulmonary physiology and disease

D. Gastrointestinal roles of PPARs

E. PPAR functions in the liver

F. Roles of PPARs in the pancreas

G. PPARs in the urinary tract physiology and pathophysiology

H. PPARs in the reproductive system

I. Bone metabolism and PPARs

J. Roles of PPARs in skeletal muscle biology

K. Skin PPARs

VI. PPARs and Drug Metabolism

VII. Molecular Aspects of PPAR Actions

A. Posttranslational control of PPARs

B. Mechanism of action

VIII. Animal Models in PPAR Research

IX. Safety of PPAR Agonists

X. The Future of PPAR Research

XI. References


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Product Details
  • ISBN-13: 9781627034197
  • Publisher: Humana Press
  • Publisher Imprint: Humana Press
  • Depth: 13
  • Height: 234 mm
  • No of Pages: 137
  • Series Title: 363
  • Sub Title: Discovery and Recent Advances
  • Width: 155 mm
  • ISBN-10: 1627034196
  • Publisher Date: 19 Apr 2013
  • Binding: Hardback
  • Edition: 2013 ed.
  • Language: English
  • Returnable: Y
  • Spine Width: 15 mm
  • Weight: 440 gr


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