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Pharmaceutical Experimental Design

Pharmaceutical Experimental Design


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About the Book

This useful reference describes the statistical planning and design of pharmaceutical experiments, covering all stages in the development process-including preformulation, formulation, process study and optimization, scale-up, and robust process and formulation development.Shows how to overcome pharmaceutical, technological, and economic constraints on experiment design!Directly comparing the advantages and disadvantages of specific techniques, Pharmaceutical Experimental DesignÂ- offers broad, detailed, up-to-date descriptions of designs and methods not easily accessible in other booksÂ- reviews screening designs for qualitative factors at different levelsÂ- presents designs for predictive models and their use in optimizationÂ- highlights optimization methods, such as steepest ascent, optimum path, canonical analysis, graphical analysis, and desirabilityÂ- discusses the Taguchi method for quality assurance and approaches for robust scaling up and process transferÂ- details nonstandard designs and mixturesÂ- analyzes factorial, D-optimal design, and offline quality assurance techniquesÂ- reveals how one experimental design evolves from anotherÂ- and more!Featuring over 700 references, tables, equations, and drawings, Pharmaceutical Experimental Design is suitable for industrial, research, and clinical pharmaceutical scientists, pharmacists, and pharmacologists; statisticians and biostatisticians; drug regulatory affairs personnel; biotechnologists; formulation, analytical, and synthetic chemists and engineers, quality assurance personnel; all users of statistical experimental design in research and development; and postgraduate and postdoctoral research workers in these disciplines.


About the Author: Lewis, Gareth A.; Mathieu, Didier; Phan-Tan-Luu, Roger


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Product Details
  • ISBN-13: 9780367447748
  • Publisher: Taylor and Francis
  • Publisher Imprint: CRC Press
  • Height: 229 mm
  • No of Pages: 512
  • Series Title: Drugs and the Pharmaceutical Sciences
  • Weight: 730 gr
  • ISBN-10: 0367447746
  • Publisher Date: 04 Dec 2019
  • Binding: Paperback
  • Language: English
  • Returnable: N
  • Spine Width: 26 mm
  • Width: 152 mm


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