Pharmacological Mechanisms in Alzheimer's Therapeutics by A. Claudio Cuello
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Pharmacological Mechanisms in Alzheimer's Therapeutics

Pharmacological Mechanisms in Alzheimer's Therapeutics


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About the Book

Overview of the Alzheimer's Disease Pathology and Potential Therapeutic Targets.- Trial Designs and Outcomes to Monitor Novel Therapeutics in Alzheimer's Disease.- The Pharmacological Treatment of Alzheimer's Disease with Cholinesterase Inhibitors and Memantine.- M1 Muscarinic Agonists: A Comprehensive Therapy Against Major Hallmarks of Alzheimer's Disease.- Cholinergic Neurodegeneration in Alzheimer's Disease: Basis for Nerve Growth Factor Therapy.- The Rationale for Glutamatergic Therapy in Alzheimer's Disease.- Secretases as Pharmacological Targets in Alzheimer's Disease.- ?-Secretase as a Target for Alzheimer's Disease.- The Rationale for an Immunological Approach to Alzheimer's Therapeutics.- Neuroinflammation, Alzheimer Disease, and Other Aging Disorders.- Nonsteroidal Anti-inflammatory Drugs (NSAIDs) and Derived A?42-Lowering Molecules for Treatment and Prevention of Alzheimer's Disease (AD).- The Potential Application of Antioxidant Agents in Alzheimer Disease Therapeutics.- Apolipoprotein E: A Potent Gene-Based Therapeutic Target for the Treatment of Sporadic Alzheimer's Disease.- Tau Pathology as a Target in Alzheimer's Therapeutics.- Design of Inhibitors of Amyloid-? Misfolding and Aggregation for Alzheimer's Therapy.- Potential Applications of Glycosaminoglycan-Related Compounds in Alzheimer's Disease.- Multifunctional Neuroprotective Drugs for the Treatment of Alzheimer's Disease.- Interpreting Clinical Studies of Putative Therapeutics for Alzheimer's Disease: The Case of Statins and NSAIDs.


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Product Details
  • ISBN-13: 9781441924469
  • Publisher: Springer
  • Publisher Imprint: Springer
  • Edition: Softcover reprint of hardcover 1st ed. 2007
  • Language: English
  • Returnable: N
  • Spine Width: 18 mm
  • Width: 156 mm
  • ISBN-10: 1441924469
  • Publisher Date: 29 Oct 2010
  • Binding: Paperback
  • Height: 234 mm
  • No of Pages: 324
  • Series Title: English
  • Weight: 530 gr


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