Poliomavírus nefrite by Soumaya Chargui - Bookswagon
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Poliomavírus nefrite

Poliomavírus nefrite


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About the Book

A nefrite poliomavírus (PVAN) é uma das complicações virais mais comuns nos transplantes renais. É em mais de 97% dos casos causados pelo vírus BK no contexto da nefrite do vírus BK e em menos de 2% causados pelo vírus JC. O PVAN leva à perda de enxertos em 30 a 80% dos casos. O diagnóstico precoce é portanto necessário para modificar o tratamento imunossupressor e evitar a perda do enxerto. O diagnóstico de PVAN é histológico e combina uma inflamação tubulo-intersticial e um efeito citopático viral sob a forma de inclusões nucleares das células tubulares. A infecção das células tubulares pode ser realçada pela evidência imuno-histoquímica da expressão do antigénio viral Sv-40. PVAN tem semelhanças histológicas com a rejeição celular aguda, mas os tratamentos resultantes são diametralmente opostos. Um requer uma diminuição da imunossupressão, enquanto o outro requer um aumento da imunossupressão. Um diagnóstico precoce e preciso é, portanto, um grande desafio.


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Product Details
  • ISBN-13: 9786205665619
  • Publisher: KS Omniscriptum Publishing
  • Publisher Imprint: Edicoes Nosso Conhecimento
  • Height: 229 mm
  • No of Pages: 52
  • Spine Width: 3 mm
  • Width: 152 mm
  • ISBN-10: 6205665611
  • Publisher Date: 21 Feb 2023
  • Binding: Paperback
  • Language: Portuguese
  • Returnable: N
  • Weight: 141 gr


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