Producción in vitro de taxoides anticancerígenos de Taxus spp.
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Producción in vitro de taxoides anticancerígenos de Taxus spp.

Producción in vitro de taxoides anticancerígenos de Taxus spp.


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About the Book

El cáncer es un término que se usa para enfermedades en las que células anormales se dividen sin control y pueden invadir otros tejidos. El cáncer es la principal causa de muerte a escala mundial. Se le atribuyen 7.6 millones de defunciones (aproximadamente el 13% del total ocurridas en todo el mundo en 2008). El taxol(R) es un fármaco anticáncer utilizado en el tratamiento de tumores sólidos como el cáncer de seno, pulmón y ovario. La técnica del cultivo de tejidos vegetales in vitro es una herramienta exitosa para la generación de cultivos de callos y células que produzcan metabolitos secundarios de gran importancia farmacéutica tales como el taxol y taxoides relacionados, sin que se destruyan los árboles de Taxus spp. Dada la importancia anterior los objetivos del presente trabajo son: indicar el origen del fármaco taxol, mecanismo de acción biológico, la biosíntesis de los taxoides, el método de extracción así como actualizar la información de los antecedentes de manera general de la producción de los principales taxoides: taxol, cefalomanina y 10 diacetil baccatina in situ y en cultivos in vitro de callos y células de Taxus spp.


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Product Details
  • ISBN-13: 9783659090752
  • Publisher: Editorial Academica Espanola
  • Binding: Paperback
  • Language: Spanish
  • Returnable: N
  • Spine Width: 5 mm
  • Width: 152 mm
  • ISBN-10: 3659090751
  • Publisher Date: 29 Jan 2015
  • Height: 229 mm
  • No of Pages: 76
  • Series Title: Spanish
  • Weight: 172 gr


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Producción in vitro de taxoides anticancerígenos de Taxus spp.
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