Préparation et évaluation de pastilles de Fexofenadine HCL à base de Jaggery
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Préparation et évaluation de pastilles de Fexofenadine HCL à base de Jaggery

Préparation et évaluation de pastilles de Fexofenadine HCL à base de Jaggery


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About the Book

L'objectif de cette étude était de développer des pastilles de chlorhydrate de fexofénadine en utilisant le Jaggery comme édulcorant. Le chlorhydrate de fexofénadine est un antihistaminique doté d'une activité antagoniste sélective des récepteurs H1 périphériques. Il est utilisé dans le traitement du rhume des foins et des symptômes allergiques similaires. Le chlorhydrate de fexofénadine est un médicament peu soluble dans l'eau et au goût amer. En raison de maux de gorge, les patients peuvent éprouver des difficultés à avaler un comprimé. Par conséquent, les pastilles constituent une forme de dosage idéale pour les patients qui ont besoin d'un soulagement rapide. Afin d'aider les patients en voyage (lorsqu'il n'y a pas d'eau disponible) et les patients qui ont des difficultés à avaler, il est nécessaire de développer des systèmes d'administration de médicaments sous forme de pastilles. Ces formes de dosage sont conçues de manière à se dissoudre dans la bouche du patient au contact de la salive pendant un certain temps, sans l'aide d'eau. Comme le médicament commence à se dissoudre dans la bouche, l'absorption du médicament commence avant qu'il n'atteigne l'estomac, ce qui permet un début d'action rapide.


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Product Details
  • ISBN-13: 9786206599449
  • Publisher: KS Omniscriptum Publishing
  • Binding: Paperback
  • Language: French
  • Returnable: N
  • Weight: 163 gr
  • ISBN-10: 6206599442
  • Publisher Date: 25 Oct 2023
  • Height: 229 mm
  • No of Pages: 68
  • Spine Width: 4 mm
  • Width: 152 mm


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