rôle des TAM dans l'invasion tumorale et les métastases
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rôle des TAM dans l'invasion tumorale et les métastases

rôle des TAM dans l'invasion tumorale et les métastases


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About the Book

De nos jours, le traitement immunitaire devient de plus en plus important dans le traitement du cancer. Les TAMs apparaissent comme des cibles attrayantes pour les stratégies thérapeutiques visant à reprogrammer leur phénotype protumoral en une activité antitumorale efficace. Il est prouvé que ces TAM favorisent activement tous les aspects de l'initiation, de la croissance et du développement des tumeurs. Les tumeurs ne doivent donc pas être traitées comme de simples agrégats de cellules cancéreuses, mais comme des structures distinctes. Le rapport altéré entre les Tregs Foxp3+ et les cellules Th17 joue un rôle important dans la pathogenèse des maladies liées à l'immunité. Nous présentons une vue d'ensemble des mécanismes responsables du recrutement des TAM et soulignons les rôles des TAM dans la régulation de l'angiogenèse tumorale, de l'invasion, des métastases, de l'immunosuppression et de la résistance aux chimiothérapies. Nous avons également tenté de décrire l'interaction entre les cellules Th17 et d'autres cellules immunitaires dans le microenvironnement tumoral, et nous évaluons les activités antitumorigènes et pro-tumorigènes potentielles des cellules Th17 et des cytokines qui leur sont associées. "Nous pensons que ces connaissances seront d'un grand intérêt pour les chercheurs qui travaillent sur la thérapie ciblant les TAM en tant que nouvelle stratégie prometteuse pour une thérapie indirecte du cancer.


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Product Details
  • ISBN-13: 9786206980155
  • Publisher: KS Omniscriptum Publishing
  • Binding: Paperback
  • Language: French
  • Returnable: N
  • Weight: 186 gr
  • ISBN-10: 6206980154
  • Publisher Date: 26 Dec 2023
  • Height: 229 mm
  • No of Pages: 84
  • Spine Width: 5 mm
  • Width: 152 mm


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rôle des TAM dans l'invasion tumorale et les métastases
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