Regulación por factores de crecimiento de la glia de Bergmann
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Regulación por factores de crecimiento de la glia de Bergmann

Regulación por factores de crecimiento de la glia de Bergmann


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About the Book

Por décadas se había considerado a las neuronas como las células protagonistas en el funcionamiento del sistema nervioso. Sin embargo, desde la descripción de las células gliales, el estudio de la fisiología del cerebro ha contemplado la existencia de las sinapsis tripartitas en las que participan tanto las neuronas pre- y post- sinápticas, así como las células gliales, en la eficiencia, magnitud y tipo de respuesta que se dará a los diferentes estímulos a los que el cerebro está expuesto. Es por esto, que el estudio de las señales a las que las células gliales son responsivas ha cobrado significativo interés en la actualidad. En el presente trabajo, se utilizó a las células gliales de Bergmann (BGC), un excelente modelo de estudio, para conocer las interacciones glía-neurona en el cerebelo y para determinar el efecto de dos factores de crecimiento en la modulación génica de este tipo celular. Con este estudio se pretende ampliar nuestro conocimiento sobre la función que los factores tróficos desempeñan en la regulación transcripcional en las BGC, así como el efecto que esto causa en la comunicación glía-neurona.


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Product Details
  • ISBN-13: 9783848457960
  • Publisher: KS Omniscriptum Publishing
  • ISBN-10: 3848457962
  • Publisher Date: 24 Apr 2012


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