Renal Cell Carcinoma by Ronald M. Bukowski - Bookswagon
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Renal Cell Carcinoma

Renal Cell Carcinoma


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Table of Contents

"Renal Cell Carcinoma: Molecular Targets & Clinical Applications, 3rd Edition"

Editors: Ronald M. Bukowski, M.D., Robert Figlin, M.D., Robert Motzer, M.D.

Ch. 1: Targeted Therapy for Metastatic Renal Cell Carcinoma: the First Ten Years

Ronald M. Bukowski, M.D., Robert Figlin, M.D., Robert Motzer, M.D.

Ch. 2: RCC: Pathologic and Molecular assessment of Targets

Ferran Algaba, M.D.

Ch. 3: Targeted Therapy for Metastatic Renal Cell Carcinoma: the First Ten Years

Stephen M. Keefe, M.D., W. Kimryn Rathmell, M.D., Ph.D., Katherine L. Nathanson, M.D.

Ch. 4: VHL and HIF in clear cell Renal Cell Carcinoma: Molecular Abnormalities and Potential Clinical Applications

Lucy Gossage, M.R.C.P., M.Sc.

Ch. 5: PBRM1: A Critical Subunit of the SWI/SNF Chromatin Remodeling Complex

Chung-Han Lee, M.D., Ph.D., Can G. Pham, Ph.D., James J. Hsieh, M.D., Ph.D.

Ch. 6: Sporadic RCC - Abnormalities in Histone Modifying Genes

Ruhee Dere, Ph.D., Thai H. Ho, M.D., Ph.D.

Ch. 7: Genetic Heterogeneity in Renal Cell Carcinoma: Clinical Implications?

Susan A.J. Vaziri, Ph.D, Mahrukh K. Ganapathi, Ph.D, Ram N. Ganapathi, Ph.D.

Ch. 8: First-Generation Tyrosine Kinase Inhibitors - Clinical Results

Han Hsi Wong, Ph.D. Tim Eisen, Ph.D., F.R.C.P.

Ch. 9: Second Generation Tyrosine Kinase Inhibitors (Pazopanib) in Renal Cell Carcinoma: Current Status

Linda Cerbone, M.D., Cora N. Sternberg, M.D., F.A.C.P.

Ch. 10: Third Generation TKIs (Axitinib, Tivozanib) in RCC: enhanced efficacy and diminished toxicity?

Hui Zhu, M.D., Ph.D., Brian I. Rini, M.D. F.A.C.P.,

Ch. 11: Anti-VEGF and VEGFR monoclonal antibodies in RCC

Bernard Escudier, M.D., Laurence Albiges, M.D.

Ch. 12: PI3-Kinase, Akt, and mTOR Inhibitors in RCC

Daniel C. Cho, M.D., James W. Mier, M.D.

Ch. 13: Carbonic anhydrase IX & Monoclonal Antibody G250: relevance as a clinical and biologic target in Renal Cell Carcinoma

Egbert Oosterwijk, Ph.D., Otto C. Boerman, Ph.D., Jeannette C. Oosterwijk-Wakka, B.Sc. Wim J. Oyen, M.D., Ph.D., Peter F. A. Mulders, M.D., Ph.D.

Ch. 14: EGFR and HER2: Relevance in Renal Cell Carcinoma

Sarathi Kalra, M.D., Eric Jonasch, M.D.

Ch. 15: The Role of Hepatocyte Growth Factor Pathway Signaling in Renal Cell Carcinoma

Fabiola Cecchi, Ph.D., Young H. Lee, Ph.D., Benedetta Peruzzi, Ph.D., Jean-Baptiste Lattouf, M.D. Donald P. Bottaro, Ph.D.

Ch. 16: Development of Resistance to Targeted Therapy: Preclinical Findings and Clinical Relevance

James W. Mier, M.D., Rupal S. Bhatt, M.D., Ph.D., David J. Panka, Ph.D., Michael B. Atkins, M.D.

Ch. 17: Development of Combination Therapy with Targeted Agents

C. Lance Cowey, M.D., Thomas E. Hutson, D.O., Pharm.D., F.A.C.P.

Ch. 18: Side Effects of Targeted Thearpy

Luis Leon, M.D., Luis Miguel Anton Aparicio, M.D., Emilio Esteban Gonzalez, M.D., Martin Lazaro Quintela, Ph.D., Sergio Vazquez Estevez, M.D.

Ch. 19: The Role of Targeted Therapy in Special Populations

James M.G. Larkin, Ph.D., F.R.C.P., Martin E. Gore, Ph.D., F.R.C.P.

Ch. 20:
About the Author:

Ronald M Bukowski MD
Emeritus Staff Physician
Cleveland Clinic Taussig Cancer Center
Professor Emeritus of Medicine
CCF Lerner College of Medicine of CWRU

Robert Figlin MD
Professor of Medicine and Biomedical Sciences
Director, Division of Hematology Oncology
Department of Medicine, Cedars-Sinai Medical Center
Associate Director for Academic Programs
Samuel Oschin Comprehensive Cancer Institute
Professor Emeritus of Medicine and Urology
David Geffen School of Medicine at UCLA

Robert Motzer MD
Attending Physician
Department of Medicine
Memorial Sloan-Kettering Cancer Center
Professor of Medicine
Weil Medical College of Cornell University


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Product Details
  • ISBN-13: 9781493950638
  • Publisher: Springer-Verlag New York Inc.
  • Binding: Paperback
  • Height: 234 mm
  • No of Pages: 613
  • Series Title: English
  • Sub Title: Molecular Targets and Clinical Applications
  • Width: 156 mm
  • ISBN-10: 1493950630
  • Publisher Date: 23 Aug 2016
  • Edition: 0003-Softcover Repri
  • Language: English
  • Returnable: Y
  • Spine Width: 32 mm
  • Weight: 920 gr


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