An Efficient, Scalable and Exact Representation of High-Dimensional Color Information Enabled Via de Bruijn Graph Search.- Identifying Clinical Terms in Free-Text Notes Using Ontology-Guided Machine Learning.- ModHMM: A Modular Supra-Bayesian Genome Segmentation Method.- Learning Robust Multi-Label Sample Specific Distances for Identifying HIV-1 Drug Resistance.- MethCP: Differentially Methylated Region Detection with Change Point Models.- On the Complexity of Sequence to Graph Alignment.- Minimization-Aware Recursive K* (MARK*): A Novel, Provable Algorithm that Accelerates Ensemble-based Protein Design and Provably Approximates the Energy Landscape.- Sparse Binary Relation Representations for Genome Graph Annotation.- How Many Subpopulations is Too Many? Exponential Lower Bounds for Inferring Population Histories.- Efficient Construction of a Complete Index for Pan-Genomics Read Alignment.- Tumor Copy Number Deconvolution Integrating Bulk and Single-Cell Sequencing Data.- OMGS: Optical Map-based Genome Scaffolding.- Fast Approximation of Frequent k-mers and Applications to Metagenomics.- De Novo Clustering of Long-Read Transcriptome Data Using a Greedy, Quality-Value Based Algorithm.- A Sticky Multinomial Mixture Model of Strand-Coordinated Mutational Processes in Cancer.- Disentangled Representations of Cellular Identity.- RENET: A Deep Learning Approach for Extracting Gene-Disease Associations from Literature.- APPLES: Fast Distance Based Phylogenetic Placement.- De Novo Peptide Sequencing Reveals a Vast Cyclopeptidome in Human Gut and Other environments.- Biological Sequence Modeling with Convolutional Kernel Networks.- Dynamic Pseudo-Time Warping of Complex Single-Cell Trajectories.- netNMF-sc: A Network Regularization Algorithm for Dimensionality Reduction and Imputation of Single-Cell Expression Data.- Geometric Sketching of Single-Cell Data Preserves Transcriptional Structure.- Sketching Algorithms for Genomic Data Analysis and Querying in a Secure Enclave.- Mitigating Data Scarcity in Protein Binding Prediction Using Meta-Learning.- Efficient Estimation and Applications of Cross-Validated Genetic Predictions.- Inferring Tumor Evolution from Longitudinal Samples.- Scalable Multi-Component Linear Mixed Models with Application to SNP Heritability Estimation.- A Note on Computing Interval Overlap Statistics.- Distinguishing Biological from Technical Sources of Variation by Leveraging Multiple Methylation Datasets.- GRep: Gene Set Representation via Gaussian Embedding.- Accurate Sub-Population Detection and Mapping Across Single Cell Experiments with PopCorn.- Fast Estimation of Genetic Correlation for Biobank-Scale Data.- Distance-Based Protein Folding Powered by Deep Learning.- Comparing 3D Genome Organization in Multiple Species Using Phylo-HMRF.- Towards a Post-Clustering Test for Didderential Expression.- AdaFDR: a Fast, Powerful and Covariate-Adaptive Approach for Multiple Hypothesis Testing.