Sinergia tra piastrine e sistema fagocitario mononucleare
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Sinergia tra piastrine e sistema fagocitario mononucleare

Sinergia tra piastrine e sistema fagocitario mononucleare


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About the Book

L'infezione da dengue è una malattia sistemica, in cui alcuni pazienti manifestano infiltrazione di plasma sanguigno nello spazio interstiziale, trombocitopenia e manifestazioni emorragiche; questa grave sindrome è chiamata febbre emorragica da dengue. I reperti ematologici comprendono aumento dell'ematocrito, trombocitopenia, prolungamento del tempo di sanguinamento e aumento del tempo di protrombina. La temperatura ritorna normale quando si verifica l'infiltrazione capillare. Lo scopo di questo lavoro è stato quello di dimostrare il sinergismo tra le piastrine e il sistema fagocitico-mononucleare durante l'infezione da virus dengue nei bambini in età scolare. Attraverso uno studio prospettico, descrittivo e longitudinale su pazienti scolastici con diagnosi di dengue. È stato dimostrato che durante la fase febbrile vi è una maggiore attività cellulare tra piastrine e monociti, con un aumento del TNF-alfa, ed esiste una relazione tra questo e gli effetti sistemici durante il decorso clinico dell'infezione. La conclusione è che le piastrine cooperano con il sistema fagocitico-mononucleare nel controllo della viremia e costituiscono un collegamento tra l'immunità innata e quella adattativa per una risposta neutralizzante.


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Product Details
  • ISBN-13: 9786206551331
  • Publisher: KS Omniscriptum Publishing
  • Binding: Paperback
  • Language: Italian
  • Returnable: N
  • Weight: 141 gr
  • ISBN-10: 6206551334
  • Publisher Date: 13 Oct 2023
  • Height: 229 mm
  • No of Pages: 52
  • Spine Width: 3 mm
  • Width: 152 mm


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