State-Of-The-Art and Emerging Technologies for Therapeutic Monoclonal Antibody Characterization Volume 3.
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State-Of-The-Art and Emerging Technologies for Therapeutic Monoclonal Antibody Characterization Volume 3.

State-Of-The-Art and Emerging Technologies for Therapeutic Monoclonal Antibody Characterization Volume 3.


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About the Book

This volume describes novel and emerging analytical technologies for analysis of proteins with the emphasis on technologies aimed to address characterization knowledge gaps and/or improve our ability to measure specified attributes with improved selectivity, sensitivity, resolution, and
throughput.

Higher order structure of proteins is a recognized important attribute of mAbs, with potential implications on stability, safety, and biological function of these large molecules. This book, the last in a series of three volumes, touches on topics ranging from X-ray crystallography, NMR,
hydrogen-deuterium exchange mass spectrometry, covalent labeling techniques, and ion mobility mass spectrometry.

About the Author:
Dr. John E. Schiel received his B.S. (2004) and Ph.D.(2009) in Chemistry from the University of Nebraska-Lincoln, and is currently a research chemist in the NIST Biomolecular Measurement Division.

Dr. Darryl L. Davis holds a doctorate in Medicinal Chemistry from the Philadelphia College of Pharmacy and Science. Currently he leads an analytical group within the discovery organization at Janssen R&D.

Dr. Oleg V. Borisov earned a B.S. degree (with honors) in Chemistry at Moscow State University (1992), and received his Ph.D. in Chemistry from Wayne State University (1997), after which he completed his post-doctoral studies at Lawrence Berkeley National Laboratories (2000) and Pacific Northwest
National Laboratories (2001). He is currently a Director at Novavax, Inc., developing methods and strategies for analysis and characterization of recombinant vaccines, based on nano- and virus-like particle technologies.


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Product Details
  • ISBN-13: 9780841230316
  • Publisher: American Chemical Society
  • Publisher Imprint: American Chemical Society
  • Depth: 38
  • Language: English
  • Returnable: Y
  • Spine Width: 18 mm
  • Volume: 3
  • Width: 155 mm
  • ISBN-10: 0841230315
  • Publisher Date: 24 Jun 2016
  • Binding: Hardback
  • Height: 94 mm
  • No of Pages: 464
  • Series Title: ACS Symposium
  • Sub Title: Defining the Next Generation of Analytical and Biophysical Techniques
  • Weight: 979 gr


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