Structural Equation Modeling for Health and Medicine

Structural equation modeling (SEM) is a very general and flexible multivariate technique that allows relationships among variables to be examined. The roots of SEM are in the social sciences. In writing this textbook, the authors look to make SEM accessible to a wider audience of researchers across many disciplines, addressing issues unique to health and medicine. SEM is often used in practice to model and test hypothesized causal relationships among observed and latent (unobserved) variables, including in analysis across time and groups. It can be viewed as the merging of a conceptual model, path diagram, confirmatory factor analysis, and path analysis. In this textbook the authors also discuss techniques, such as mixture modeling, that expand the capacity of SEM using a combination of both continuous and categorical latent variables. Features: Basic, intermediate, and advanced SEM topics Detailed applications, particularly relevant for health and medical scientists Topics and examples that are pertinent to both new and experienced SEM researchers Substantive issues in health and medicine in the context of SEM Both methodological and applied examples Numerous figures and diagrams to illustrate the examples As SEM experts situated among clinicians and multidisciplinary researchers in medical settings, the authors provide a broad, current, on the ground understanding of the issues faced by clinical and health services researchers and decision scientists. This book gives health and medical researchers the tools to apply SEM approaches to study complex relationships between clinical measurements, individual and community-level characteristics, and patient-reported scales.

Table of Contents:
Part I Introduction to Concepts and Principles of Structural Equation Modeling for Health and Medical Research 1. Introduction and Brief History of Structural Equation Modeling for Health and Medical Research 2. Vocabulary, Concepts and Usages of Structural Equation Modeling Part II Theory of Structural Equation Modeling 3 The Form of Structural Equation Models 4 Model Estimation and Evaluation 5 Model Identifiability and Equivalence Part III Applications and Examples of Structural Equation Modeling for Health and Medical Research 6 Choosing Among Competing Specifications 7 Measurement Models for Patient-Reported Outcomes and Other Health-related Outcomes 8 Exploratory Factor Analysis 9 Mediation and Moderation 10 Measurement Bias, Multiple Indicator Multiple Cause Modeling and Multiple Group Modeling 11 Latent Class Analysis 12 Latent Profile Analysis 13 Structural Equation Modeling with Longitudinal Data 14 Growth Mixture Modeling 15 Special Topics