.- 1 Immunological Background
.- 2 Classification of Vaccines
.- 3 Aluminum Adjuvants - Basic Concepts and Progress in Understanding
.- 4 Emulsions as Vaccine Adjuvants
.- 5 The application of liposomes as vaccine adjuvants
.- 6 Developing Bilayer-based Delivery Systems for Oral Delivery of Subunit Vaccines
.- 7 Cubosomes - Structure, Preparation and Use as an Antigen Delivery System
.- 8 ISCOMs as a Vaccine Delivery System
.- 9 Virus-like Particles, a Versatile Subunit Vaccine Platform
.- 10 Polymeric Particulates for Subunit Vaccine Delivery
.- 11 Gels as Vaccine Delivery Systems
.- 12 Implants as Sustained Release Delivery Devices for Vaccine Antigens
.- 13 Dendritic Cell-based Vaccines
.- 14 Parenteral Vaccine Administration - Tried and True
.- 15 Nasal Administration of Vaccines
.- 16 Pulmonary Administration of Subunit Vaccines
.- 17 Vaginal Delivery of Subunit Vaccines
.- 18 Transcutaneous Administration
.- 19 Pharmaceutical Analysis and Quality Control of Vaccines
.- 20 The Physical Analysis of Vaccines
.- 21 Characterizing the Association between Antigens and Adjuvants.
About the Author: Associate Professor Camilla Foged is Head of the Vaccine Design and Delivery Group in Section of Biologics, Department of Pharmacy, University of Copenhagen, Copenhagen, Denmark. She has an MSc in Biochemistry from University of Copenhagen. Dr. Foged attained her PhD from The Danish University of Pharmaceutical Sciences. Her main research interest is advanced drug delivery aiming at designing new vaccine and nucleic acid delivery systems to improve therapy. Her group efficiently has addressed drug delivery challenges with cutting edge technologies, which has enabled high impact publications and innovative solutions in drug delivery. The group's research goal is to improve disease prevention and treatment by designing nanoparticulate vaccine and nucleic acid formulations through in-depth knowledge of how the physicochemical properties of the particles affect their interaction with the environment, e.g. in formulation, in vitro and in vivo. Dr. Foged is interested in lipid- and polymer-based nanoparticulate delivery systems using various approaches for targeting and membrane destabilization.
Professor Thomas Rades is the Research Chair in Pharmaceutical Design and Drug Delivery in the Department of Pharmacy, University of Copenhagen, Copenhagen, Denmark. Dr. Rades obtained his PhD from the University of Braunschweig, Germany, and he has developed an international reputation for his research on solid dosage forms as well as in vaccine delivery using nanoparticulate systems. Research in both areas aims to improve drug therapy through appropriate formulation and physicochemical characterisation of medicines and vaccines. It combines physical, chemical, and biological sciences and technology to optimally formulate drugs and vaccines for human and veterinary uses. Professor Rades has published more than 270 papers in international peer review journals.
Professor Yvonne Perrie is Head of Pharmacy and Chair in Drug Delivery within Aston Pharmacy School, Aston University, Birmingham, UK. Dr. Perrie attained her PhD from the University of London under the supervision of Professor Gregoriadis. Her research is multi-disciplinary and is focused on the development of drug carrier systems to facilitate the delivery of drugs and vaccines, providing practical solutions for current healthcare problems. Dr. Perrie is a Fellow of the Society of Biology and an Eminent Fellow of the Academy of Pharmaceutical Sciences. Externally, she is a Director-at-large for the Controlled Release Society and Editor of the Controlled Release Society Newsletter. She is Editor-in-Chief of the Journal of Liposome Research and Pharmaceutics, and she is associate editor for the Journal of Drug Targeting and the Journal of Pharmacy and Pharmacology.
Professor Sarah Hook is the Professor of Biopharmaceutics of the School of Pharmacy at the University of Otago, Dunedin, New Zealand, where she obtained her PhD in immunology. Her area of interest is in the development and testing (physical, chemical and immunological) of novel formulations for the delivery of small and large molecule drugs for the prevention and treatment of both communicable and non-communicable diseases.