Synthèse de dérivés de la cinnoline catalysée par l'acide de Lewis
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Synthèse de dérivés de la cinnoline catalysée par l'acide de Lewis

Synthèse de dérivés de la cinnoline catalysée par l'acide de Lewis


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About the Book

Une synthèse efficace des 4-benzyl cinnolines à partir de l'hydrazone aryl phényl allylidène est décrite. Dans ce rapport, le chlorure stanneux est utilisé comme catalyseur d'acide de Lewis et des solvants polaires et non polaires sont utilisés pour la synthèse. Cette méthode devrait être plus avantageuse que les autres méthodes de synthèse des anneaux de cinnoline signalées en raison de son faible coût, de son meilleur rendement et de ses conditions de réaction bénignes. Utiliser le chlorure stanneux comme catalyseur d'acide de Lewis dans la réaction d'addition de Michael de l'indole avec divers dérivés nitrés du styrène. Il semblerait que le chlorure stanneux présente un avantage par rapport à d'autres catalyseurs d'acide de Lewis courants, pour lesquels une quantité catalytique d'acide de Bronsted est également nécessaire pour une activité catalytique efficace. En observant l'efficacité du MW dans la synthèse organique, nous avons planifié l'irradiation du MW pour certaines de nos réactions.


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Product Details
  • ISBN-13: 9786207516124
  • Publisher: KS Omniscriptum Publishing
  • Binding: Paperback
  • Language: French
  • Returnable: N
  • Weight: 145 gr
  • ISBN-10: 6207516125
  • Publisher Date: 07 May 2024
  • Height: 229 mm
  • No of Pages: 56
  • Spine Width: 3 mm
  • Width: 152 mm


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