1. Conceptual Challenges in the Theoretical Foundations of Systems Biology
Marta Bertolaso and Emanuele Ratti
2. An Integrative Approach toward Biology, Organism
s, and Cancer Carlos Sonnenschein and Ana M. Soto
3. Conceptual Challenges of the Systemic Approach in Understanding Cell Differentiation
Andras Pald
i
4. A Primer on Mathematical Modeling in the Study of Organisms and their Parts
Maël Montévil
5. The Search for System's Parameters Alessandro Giuliani
6
. Inverse Problems in Systems Biology: A Critical Review Rodolfo Guzzi, Teresa Colombo, and Paola Paci
7. Systems Biology Approach and Mathematical Modeling for Analyzing Phase-space Switch during Epithe
lial-mesenchymal Transition Chiara Simeoni, Simona Dinicolab, Alessandra Cucina, Corrado Mascia, and Mariano Bizzarri
8.
Parameters Estimation in Phase-space Landscape Reconstruction of Cell Fate; A Systems Biology Approach S. Montero, R.R. Martin, R. Mansilla, G. Cocho, and J.M. Nieto-Villar
9. Complexity of Biochemical and Genetic Responses Reduced using Simple Theoretical Models Kumar Selvarajoo
10. Systems Biology Modelling of Non-linear Cancer Dynamics
Christian Cherubini, Simonetta Filippi, and Alessandro Loppini
11. Endogenous Molecular-cellular Network Cancer Theory: A Systems Biology Approach
Gaowei Wang, Ruoshi Yuan, Xiaomei Zhu, and Ping Ao
12. A Network-based Integrative Workflow to Unravel Mechanisms Underlying Disease Progression
Faiz M. Khan, Mehdi Sadeghi, Shailendra K. Gupta, and Olaf Wolkenhauer
13. Spatiotemporal Fluctuation Analysis of Molecular Diffusion Laws in Live-cell Membranes
Francesco Cardarelli
14. A Method for Cross-species Visualization and Analysis of RNA-sequence Data
Stephen A. Ramsey
15. Multi Agent Simulations of Population Behavior (A Promising Tool for Systems Biology)
Alfredo Colosimo
16.
Metabolomics: Challenges and Opportunities in Systems Biology Studies Luca Casadei, Mariacristina Valerio, and Cesare Manetti
17. Systems Biology-driven Hypotheses Tested In Vivo: The Need to Advancing Molecular Imaging Tools Garima Verma, Alessandro Palombo, Maura Grigioni, Morena La Monaca, and Giuseppe D'Avenio