Textbook of Medical Physiology_3rd Edition

Salient Features Complete and up-to-date text incorporating recent advances. Illustrated by more than 1100 clear line diagrams. Complemented with numerous tables and flowcharts for quick comprehension. Applied aspects, highlighted in the boxes, have been expanded and updated with recent molecular concepts on pathophysiology, advances in investigations and therapeutic principles. Additional important information has been highlighted as important notes. The above features of this book make it an indispensable text for postgraduates in Physiology. Candidate preparing for PG entrance examination would also find it as an authentic reference source. Complimentary access to full e-book.

Table of Contents:
PART I General Physiology SECTION 1 General Physiology 1.1 Functional Organization, Composition and Internal Environment of Human Body Functional Organization of the Human Body Body Composition Internal Environment and Homeostasis 1.2 The Cell Physiology Cell Structure The Cell Membrane intercellular Junctions 1.3 Transport through Cell Membrane Passive Transport Active Transport Vesicular Transport Other Transport Processes 1.4 Membrane Potential Introduction Genesis of Membrane Potential Recording of Membrane Potential 1.5 Genetics: An Overview Structural and Functional Characteristics of Substrate for Genetics Applied Genetics PART II Systemic Physiology SECTION 2 Nerve Muscle Physiology 2.1 The Nerve Functional Anatomy Biological Activities Electrical Properties of Nerve Fibre Physiological Properties of Nerve Fibres Nerve Fibre Types Degeneration and Regeneration of Neurons Factors Promoting Neuronal Growth 2.2 Neuromuscular Junction Structure of Neuromuscular Junction Neuromuscular Transmission Drugs Affecting and Disorders of Neuromuscular Junction Applied Aspects 2.3 Skeletal Muscle Introduction Functional Anatomy and Organization Process of Muscle Excitability and Contractility Characteristics of Muscle Excitability and Contractility Some Characteristics of the Skeletal Muscles in the Intact Body Electromyography and Common Disorders of Muscles Applied Aspects Source of Energy and Metabolic Phenomenon During Muscle Contraction 2.4 Smooth Muscle and Cardiac Muscle Smooth Muscle Cardiac Muscle Comparison of Skeletal, Smooth and Cardiac Muscles SECTION 3 Blood and Immune System 3.1 Plasma and Plasma Proteins Plasma Plasma Proteins 3.2 Red Blood Cells and Anaemias Characteristic Features of Red Blood Cells Formation of Red Blood Cells Haemoglobin Red Cell Fragility Lifespan and Fate of Red Blood Cells Bilirubin and Jaundice Anaemias 3.3 White Blood Cells White Blood Cell Types and their Counts Formation of White Blood Cells Morphology, Functions, Lifespan and Variations in Counts of Wbcs Applied Aspects Applied Aspects 3.4 Immune Mechanisms Introduction Architecture (Components) of Immune System Immunity Antigens Antibodies Development of Immune Response Other Immune Mechanism-Related Aspects 3.5 Platelets, Haemostasis and Blood Coagulation Platelets Haemostasis Blood Coagulation Clotting Factors Mechanism of Coagulation Antihaemostatic Mechanisms Bleeding Disorders 3.6 Blood Groups and Blood Transfusion Blood Groups Blood Transfusion SECTION 4 Cardiovascular System 4.1 Functional Anatomy of Heart and Physiology of Cardiac Muscle Functional Anatomy of Heart Physiology of Cardiac Muscle 4.2 Origin and Spread of Cardiac Impulse and Electrocardiography Origin and Spread of Cardiac Impulse Electrocardiography Applied Aspects 4.3 Heart as a Pump: Cardiac Cycle, Cardiac Output and Venous Return Cardiac Cycle Cardiac Output and Venous Return 4.4 Dynamics of Circulation: Pressure and Flow of Blood and Lymph Introduction Functional Organization and Structure of Vascular System Haemodynamics Pressure and Flow in Various Functional Segments of Systemic Vascular Tree Blood Pressure 4.5 Cardiovascular Regulation Introduction Neural Control Mechanism Humoral Control Mechanisms Local Control Mechanisms 4.6 Regional Circulation Introduction Coronary Circulation Applied Aspects Cerebral Circulation Cutaneous Circulation Skeletal Muscle Circulation Splanchnic Circulation 4.7 Cardiovascular Homeostasis in Health and Disease Cardiovascular Homeostasis in Health Cardiovascular Homeostasis in Diseases SECTION 5 Respiratory System 5.1 Respiratory Tract: Structure and Functions Functional Anatomy Functions of the Respiratory System 5.2 Pulmonary Ventilation Introduction Mechanics of Pulmonary Ventilation Lung Volumes and Capacities Pulmonary Elastance and Compliance Work of Breathing 5.3 Pulmonary Circulation Functional Anatomy Characteristic Features of Pulmonary Circulation Functions of Pulmonary Circulation Regulation of Pulmonary Blood Flow 5.4 Pulmonary Diffusion Introduction Physics of Gas Diffusion and Gas Partial Pressures Alveolar Ventilation Alveolar Ventilation-Perfusion Ratio Alveolar Air Diffusion of Gases Through the Respiratory Membrane 5.5 Transport of Gases Introduction Transport of Oxygen Transport of Carbon Dioxide 5.6 Regulation of Respiration Introduction Neural Regulation of Respiration Afferent Impulses to Respiratory Centres Chemical Regulation of Respiration 5.7 Respiration: Applied Aspects Introduction Respiratory Adjustments to Stresses in Health Disturbances of Respiration Artificial Respiration and Cardiopulmonary Resuscitation Pulmonary Function Tests SECTION 6 Excretory System 6.1 Kidneys: Functional Anatomy and Blood Flow Functional Anatomy of Kidneys Renal Blood Flow 6.2 Mechanism of Urine Formation: Glomerular Filtration and Tubular Transport Introduction Glomerular Filtration Tubular Reabsorption and Secretion 6.3 Concentration, Dilution and Acidification of Urine Concentration and Dilution of Urine: A Mechanism to Regulate Urine Volume and Osmolality Acidification of Urine 6.4 Regulation of Body Fluid Osmolality, Composition and Volume Introduction Body Fluid Compartments Control of Body Fluid Osmolality Regulation of Extracellular Fluid Volume and Composition Defence of Specific Ion Composition Disturbances of Volume and Concentration of Body Fluid 6.5 Applied Renal Physiology Including Renal Function Tests Pathophysiology of Common Renal Disorders Diuretics Renal Function Tests Dialysis and Renal Transplantation 6.6 Physiology of Micturition Urinary Bladder and Urethra Physiology of Micturition Abnormalities of Micturition SECTION 7 Gastrointestinal System 7.1 Functional Anatomy and General Principles of Functions of Gastrointestinal System Functional Anatomy General Principles of Gastrointestinal Functions 7.2 Physiological Activities in Mouth, Pharynx and Oesophagus Introduction Mastication Lubrication of Food by Saliva Deglutition (Swallowing) Applied Aspects 7.3 Physiological Activities in Stomach Functional Anatomy Physiology of Gastric Secretion Physiology of Gastric Motility Functions of Stomach Applied Aspects 7.4 Pancreas, Liver and Gall Bladder Pancreas Liver and Gall Bladder 7.5 Physiological Activities in Small Intestine Functional Anatomy Small Intestinal Secretions Motility of Small Intestine Functions of Small Intestine Applied Aspects 7.6 Physiological Activities in Large Intestine Functional Anatomy Large Intestinal Secretions and Bacterial Activity Motility of Large Intestine Defaecation Functions of Large Intestine Applied Aspects 7.7 Digestion and Absorption Digestion and Absorption of Carbohydrates Applied Aspects Digestion and Absorption of Proteins Applied Aspects Digestion and Absorption of Fats Absorption of Water, Electrolytes, Minerals and Vitamins Applied Aspects SECTION 8 Endocrinal System 8.1 General Principles of Endocrinal System Hormones: Definition and Classification Hormones: General Considerations Hormone: Receptors and Mechanism of Action Measurement of Hormones 8.2 Endocrinal Functions of Hypothalamus and Pituitary Gland Introduction and Functional Anatomy Endocrinal Aspects of Hypothalamus Anterior Pituitary Hormones Posterior Pituitary Hormones Applied Aspects 8.3 Thyroid Gland Functional Anatomy Thyroid Hormones Applied Aspects of Thyroid Hormones 8.4 Endocrinal Control of Calcium Metabolism and Bone Physiology Introduction Calcium, Phosphorus and Magnesium Metabolism Bone Physiology Calcitropic Hormones Applied Aspects 8.5 Adrenal Glands Functional Anatomy Hormones of Adrenal Cortex Mineralocorticoids Applied Aspects Hormones of Adrenal Medulla 8.6 Pancreatic and Gastrointestinal Hormones Endocrine Pancreas Applied Aspects Gastrointestinal Hormones 8.7 Endocrinal Functions of Other Organs and Local Hormones Hormones of the Heart Hormones of the Kidney Pineal Gland Thymus Local Hormones SECTION 9 Reproductive System 9.1 Sexual Growth and Development Prepubertal Sexual Growth and Development Applied Aspects Puberty and Adolescence Applied Aspects 9.2 Male Reproductive Physiology An Overview of Male Reproductive System Functional Anatomy of Testes Functions of Testes Control of Androgen Secretion Applied Aspects 9.3 Female Reproductive Physiology An Overview of Female Reproductive System Ovaries Female Sexual Cycle Applied Aspects 9.4 Physiology of Coitus, Pregnancy and Parturition Physiology of Coitus Physiology of Pregnancy Physiology of Parturition Applied Aspects 9.5 Physiology of Lactation Development and Functional Anatomy of Breast Physiology of Lactation 9.6 Physiology of Contraception Introduction Contraceptive Methods in Females Contraceptive Methods in Males SECTION 10 Nervous System 10.1 Physiological Anatomy, Functions and Lesions of Spinal Cord and Brainstem Physiological Anatomy and Functions of Spinal Cord Physiological Anatomy and Functions of Brainstem Tracts of Spinal Cord and Brainstem Applied Aspects Lesions of Spinal Cord and Brainstem 10.2 Physiological Anatomy, Functions and Lesions of Cerebellum and Basal Ganglia Cerebellum Applied Aspects Basal Ganglia 10.3 Physiological Anatomy, Functions and Lesions of Thalamus and Hypothalamus Thalamus Hypothalamus 10.4 Physiological Anatomy and Functions of Cerebral Cortex and White Matter of Cerebrum Cerebral Cortex White Matter of Cerebrum 10.5 Autonomic Nervous System Anatomical Considerations Physiological Considerations Applied Aspects 10.6 Meninges, Cerebrospinal Fluid, Blood-Brain Barrier and Cerebral Blood Flow Meninges of the Brain Cerebrospinal Fluid Blood-Brain Barrier and Blood-CSF Barrier Cerebral Blood Flow 10.7 Synaptic Transmission Synapse: Definition and Types Chemical Synapse Neurotransmitters 10.8 Somatosensory System General Sensory Mechanism Somatosensory System 10.9 Somatic Motor System Introduction Components of Somatic Motor Control System Skeletal Muscles: the Effector Organ of Somatic Motor System Applied Aspects Refl ex Activity Regulation of Posture Vestibular Apparatus and Equilibrium 10.10 Limbic System and Physiology of Emotional, Behavioural and Motivational Mechanisms Limbic System Physiology of Emotions Physiology of Motivation Monoaminergic Neuronal Tracts and Physiological Basis of Psychotic Disorders Applied Aspects 10.11 Reticular Formation, Electrical Activity of the Brain, and Alert Behaviour and Sleep Reticular Formation and Reticular-Activating System Electrical Activity of the Brain Wakefulness and Sleep Applied Aspects 10.12 Some Higher Functions of Nervous System Language and Speech Applied Aspects Learning and Memory Higher Intellectual Functions of the Prefrontal Association Cortex SECTION 11 Special Senses 11.1 Sense of Vision Introduction and Functional Anatomy Maintenance of Clear Refractive Media of the Eye The Image Forming Mechanism Applied Aspects Physiology of Vision Applied Aspects Field of Vision and Binocular Vision Applied Aspects Applied Aspects Physiology of Ocular Motility Aqueous Humour and Intraocular Pressure Physiology of Pupil Applied Aspects 11.2 Sense of Hearing Functional Anatomy Auditory Pathways Physiology of Hearing Conduction of Sound Waves Transduction of Sound Waves Neural Transmission of Signals Neural Processing of Auditory Information Applied Aspects 11.3 Chemical Senses: Smell and Taste The Sense of Smell Applied Aspects Applied Aspects PART III Specialized Integrative Physiology SECTION 12 Specialized Integrative Physiology 12.1 Physiology of Exercise and Sports Introduction Responses To Exercise Effects of Training 12.2 Environmental Physiology High-Altitude Physiology Physiology of High Atmospheric Pressure 12.3 Physiology of Acid-Base Balance General Considerations Maintenance of Blood pH Acid-Base Disorders Analysis and Clinical Evaluation of Acid-Base Disorders 12.4 Physiology of Body Temperature Regulation Body Temperature Heat Balance Regulation of Body Temperature Applied Aspects 12.5 Physiology of Growth and Behavioural Development Growth and Development Behavioural Development 12.6 Physiology of Fetus, Neonate and Childhood Introduction Role of Placenta in Fetal Physiology Systemic Physiology of Fetus, Newborn and Childhood Applied Aspect Applied Aspects 12.7 Geriatric Physiology Introduction Age-Related Changes In Different Organ Systems Theories of Ageing Modulating the Process of Ageing Index