Transplantation de cellules par voie intraveineuse ou intrapéritonéale chez des rats diabétiques
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Transplantation de cellules par voie intraveineuse ou intrapéritonéale chez des rats diabétiques

Transplantation de cellules par voie intraveineuse ou intrapéritonéale chez des rats diabétiques


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About the Book

Le diabète de type 1 est une maladie métabolique dévastatrice qui peut entraîner la progression de complications chroniques telles que la cécité, l'insuffisance rénale, les maladies cardiovasculaires, les accidents vasculaires cérébraux, la neuropathie et le dysfonctionnement vasculaire, etc. Le remplacement des îlots de Langerhans d'un patient diabétique est le seul traitement du diabète de type І qui permette d'obtenir un état normoglycémique constant et indépendant de l'insuline et d'éviter les épisodes d'hypoglycémie. Cependant, la transplantation d'îlots a été entravée par la pénurie mondiale d'îlots prêts à être transplantés, le rejet immunitaire et les attaques récurrentes contre les îlots par l'auto-immunité sous-jacente. Aujourd'hui, la production in vitro de nouvelles cellules productrices d'insuline à partir de cellules non-β suscite un intérêt généralisé. Il existe peu de recherches comparant l'efficacité de diverses méthodes de transplantation de cellules souches mésenchymateuses (CSM). Dans ce contexte, l'objectif de cette étude était de comparer l'efficacité thérapeutique de la transplantation de CSM par deux méthodes différentes (injection dans la veine de la queue et injection intrapéritonéale) dans le traitement des rats diabétiques induits par la streptozotocine (STZ) in vivo.


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Product Details
  • ISBN-13: 9786206659488
  • Publisher: KS Omniscriptum Publishing
  • Binding: Paperback
  • Language: French
  • Returnable: N
  • Weight: 141 gr
  • ISBN-10: 6206659488
  • Publisher Date: 13 Nov 2023
  • Height: 229 mm
  • No of Pages: 52
  • Spine Width: 3 mm
  • Width: 152 mm


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Transplantation de cellules par voie intraveineuse ou intrapéritonéale chez des rats diabétiques
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Transplantation de cellules par voie intraveineuse ou intrapéritonéale chez des rats diabétiques
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