Tumorangiogenese und antiangiogene Therapie
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Tumorangiogenese und antiangiogene Therapie

Tumorangiogenese und antiangiogene Therapie


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About the Book

Die große Mehrheit der Primärtumore ist gutartig und für den Wirt harmlos. Die Wahrscheinlichkeit, dass ein gutartiger Tumor zum Tod führt, ist daher sehr gering oder selten. Die meisten krebsbedingten Todesfälle sind auf die Metastasierung zurückzuführen. Die Krebsmetastasierung ist ein komplexes, mehrstufiges Phänomen, das ausschließlich bösartigen Tumoren zu eigen ist. Bei der Metastasierung verlassen Krebszellen den ursprünglichen Tumorort (d. h. den Primärtumor) und wandern über die Blutbahn oder das Lymphsystem in andere Teile des Körpers. Der neue Tumor in einem entfernten Zielorgan wird als sekundärer oder metastatischer Tumor bezeichnet. In den meisten Fällen haben Patienten mit einem lokalisierten Primärtumor eine bessere Prognose als Patienten mit einem metastasierten Tumor. Der metastatische Prozess und das Tumorwachstum sind von der Angiogenese abhängig. Diese Art der Angiogenese ist durch eine abnorme Gefäßentwicklung gekennzeichnet. Die dabei entstehenden Blutgefäße entsprechen nicht genau den normalen Blutgefäßen. Sie sind nicht in endgültige Venolen, Arteriolen und Kapillaren gegliedert. Sie sind undichter als normale Gefäße. Die Komplexität des angiogenen Prozesses, an dem sowohl positive als auch negative Regulatoren beteiligt sind, bietet eine Reihe von Ansatzpunkten für die Therapie.


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Product Details
  • ISBN-13: 9786207435920
  • Publisher: KS Omniscriptum Publishing
  • Binding: Paperback
  • Language: German
  • Returnable: N
  • Weight: 141 gr
  • ISBN-10: 6207435923
  • Publisher Date: 26 Apr 2024
  • Height: 229 mm
  • No of Pages: 52
  • Spine Width: 3 mm
  • Width: 152 mm


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