UICC Manual of Clinical Oncology

The Manual of Clinical Oncology, Ninth Edition, published with the International Union Against Cancer (UICC), provides a concise, accessible and feasible reference covering state of art multidisciplinary clinical oncology in order to meet the needs of clinicians caring for cancer patients throughout the world. Edited by world-renowned practising oncologists and written by key opinion leaders, this book contains authoritative and up-to-date information on cancer detection, diagnosis and treatment alongside topics such as survivorship, special populations and palliative care. Remodelled and revised for the ninth edition to provide practical information to oncology workers, the UICC Manual of Clinical Oncology is structured in two parts. Part 1 covers general principles of cancer diagnosis and management with additional attention to special settings in oncology, including supportive care and survivorship, and Part 2 covers site-specific multidisciplinary cancer management. The edition includes up-to-date summaries of all treatment modalities (medical, surgical and radiation) for all tumour sites. It also contains the latest TNM classifications outlined in the TNM Classification of Malignant Tumours. The ninth edition includes: Practical presentation with bullet points, tables, and flow charts intended to facilitate quick reference for day-to-day clinical practice in busy oncology environments, Representation of multidisciplinary care for site specific management, Evidence-based approaches to management, including specific treatment recommendations and investigations guided by clinical practice guidelines, State of art evidence-based recommendations that take into consideration the lack of availability of certain medications or resources, as well as practice variations, in different and remote regions of the world, and Contemporary topics on cancer treatment, such as cancer informatics, evidence levels, principles of prognostication, survivorship and cancer in pregnancy. Oncologists, oncologists-in-training, nurses working with cancer patients and other health professionals responsible for treating and caring for those with cancers will find the UICC Manual of Clinical Oncology an indispensable and comprehensive resource.

Table of Contents:
Foreword x Preface xi About the Editors xiii Contributors xvi PART 1 General principles of cancer diagnosis and management 1 Principles of knowledge generation and translation 1 – Cancer epidemiology 3 2 – Levels of evidence, guidelines and standards 12 3 – Prognosis and classification of cancer 23 4 – Principles of cancer staging 34 5 – Assessment of treatment outcome 40 6 – Cancer informatics 53 Principles of cancer diagnosis 7 – Imaging 63 8 – Pathology 83 Principles of treatment 9 – Principles of surgery 98 10 – Principles of radiotherapy 108 11 – Principles of systemic therapy 124 Special settings, supportive care and survivorship 12 – Treatment in pregnancy 134 13 – Treatment in the elderly 139 14 – Oncology emergencies 145 15 – Supportive care during curative treatment 155 16 – Pain management in cancer 168 17 – Palliative care 174 18 – Survivorship 184 19 – Rehabilitation 194 PART 2 Site-specific multidisciplinary cancer management 203 Thoracic malignancies 20 – Lung 205 Breast 21 – Breast 221 Gastrointestinal malignancies 22 – Liver 241 23 – Biliary tract and pancreas 263 23.1 – Biliary tract 263 23.2 – Pancreas 270 24 – Oesophagus 280 25 – Stomach 297 26 – Colon, rectum and anus 308 26.1 – Colon and rectum 308 26.2 – Anus 327 Genitourinary malignancies 27 – Prostate 333 28 – Bladder and other urothelium 343 29 – Kidney 354 30 – Testicular germ cell tumours 368 31 – Penis 384 Haematological malignancies 32 – Lymphoma 392 33 – Myeloma 415 34 – Leukaemia 427 Gynaecological cancers 35 – Cervix 449 36 – Uterus 467 37 – Ovary and fallopian tube 479 Head and neck cancer 39 – General principles of head and neck cancer management 503 40 – Nasopharynx 512 41 – Oral cavity 524 42 – Larynx and hypopharynx 542 43 – Oropharynx 559 44 – Major salivary glands 571 45 – Nasal cavity and paranasal sinus 586 46 – Head and neck unknown primary 597 Endocrine tumors 47 – Pituitary 609 48 – Thyroid 626 49 – Adrenal tumours 641 50 – Neuroendocrine tumours 656 Dermatological cancer 51 – Skin: Basal cell carcinoma, squamous cell carcinoma and Merkel cell carcinoma 674 52 – Melanoma 689 Central nervous system and ocular cancers 53 – Central nervous system 706 54 – Eye: Choroidal melanoma, retinoblastoma, ocular adnexal lymph Sarcoma 55 – Bone (osteosarcoma) 745 56 – Soft tissue 754 Childhood malignancies 57 – Paediatric tumors 768 Specific cancer situations 58 – Cancer of unknown primary (no 59 – HIV and transplant-related neoplasms 797 59.1 – HIV-related neoplasms 797 59.2 – Post-transplantation lymphoproliferative disease 809 59.3 – Cancer following solid organ transplantation 812 Index 815