Études QSAR et d'amarrage de dérivés d'urée en tant qu'agents antituberculeux
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Études QSAR et d'amarrage de dérivés d'urée en tant qu'agents antituberculeux

Études QSAR et d'amarrage de dérivés d'urée en tant qu'agents antituberculeux


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About the Book

L'augmentation de la survie humaine est principalement due aux médicaments et à ceux qui les ont découverts. Comme dans tous les domaines scientifiques, l'histoire des produits pharmaceutiques est également connue pour les idées, les connaissances et les outils disponibles qui ont fait progresser nos connaissances. Mycobacterium tuberculosis est un agent pathogène bactérien qui est devenu une menace mondiale en raison de l'émergence de souches de mycobactéries résistantes, ce qui se traduit par une résistance multiple aux médicaments (MDR-TB), une résistance étendue aux médicaments (XDR-TB) et une résistance totale aux médicaments (TDR-TB). La conception de médicaments assistée par ordinateur vise à accroître la rapidité et l'efficacité du processus de découverte de médicaments et à rendre le processus de conception de médicaments plus rationnel. Les modèles de régression QSAR établissent une relation linéaire entre un ensemble de descripteurs moléculaires de produits chimiques et l'activité biologique. La cartographie des pharmacophores traite de la disposition spatiale des groupes fonctionnels essentiels à l'activité biologique. Le docking est utilisé pour établir l'interaction médicament-récepteur nécessaire à l'obtention d'une réponse biologique. Les dérivés de l'urée ont été analysés par CADD pour développer des médicaments antituberculeux puissants.


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Product Details
  • ISBN-13: 9786206967194
  • Publisher: KS Omniscriptum Publishing
  • Binding: Paperback
  • Language: French
  • Returnable: N
  • Weight: 177 gr
  • ISBN-10: 6206967190
  • Publisher Date: 20 Dec 2023
  • Height: 229 mm
  • No of Pages: 80
  • Spine Width: 5 mm
  • Width: 152 mm


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